MSG and Migraine

MSG is a migraine trigger according to the Journal of the American Medical Association:

http://www.hmc.psu.edu/childrens/healthinfo/articles/migraines.pdf

The fact that MSG is a migraine trigger is not surprising when you consider that glutamate - the business end of MSG is a calcium channel opener.  (Most blood pressure lowering medications are calcium channel blockers).  MSG therefore affects blood vessel vasoconstriction. 

Also, there is a theory that migraines are caused by inflammation in the mouth area pressing against nerves in the head.  It must be mentioned here that glutamate increases histamine response although it does not initiate an immune antigen response.  Histamine induces inflammation.

These two items - blood vessel vasoconstriction and inflammation are implicated in migraines and are also caused by ingestion of MSG.

Below is a story about a physician who treats his migraine patients with an MSG-free diet:

http://www.npr.org/templates/story/story.php?storyId=5364970

 

 

 

  

 

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