MSG and Autism

Autism, Vaccines, Epilepsy, and MSG

Although epilepsy patients are advised not to eat foods containing MSG, due to their interference with anti-seizure drugs, like lamotrogine and topiramate (both glutamate blockers), MSG is listed as an official vaccine additive on the official government CDC website:

http://www.cdc.gov/vaccines/vac-gen/additives.htm

We honestly don't understand how public health policy "experts" can say that vaccines have nothing to do with seizures suffered by many children after receiving vaccines with MSG in them.  The fact that 30% of children with autism also suffer from epilepsy should be a red flag. http://www.epilepsyfoundation.org/epilepsyusa/yebeh/upload/autismandepilepsy.pdf

The fact that many parents with children who regressed after vaccination report seizures shortly after vaccination should be enough to spur thorough investigation.

Breaking NEWS:

MARCH 19, 2013 - It is now reported that the autism rate is 1 in 50 children in the US and 1 in 38 children in South Korea. The rate has essentially risen 200-fold since the 1940's.  In 2006 which showed glutamate was elevated in the brains of autistic males. In 2007 it was discovered that some autism genes code for glutamate synapses. Currently, nutrition experts teaching parents to cook for autistic children, specifically avoid free glutamate and MSG in the diet as well as gluten and casein, which are also sources of free glutamate.  Unfortunately, the MMR vaccine currently contains free glutamate as a preservative and was added to these vaccines in 1988 after the patent was granted in 1982.

FEBRUARY 5, 2013  - Exciting finding so far, and a clue we may be understanding what is going on here.
The latest gene deletion found in boys where two boys in the family have autism is a sex-linked mutation - the gene is found on the X chromosome - which means boys only get one copy of this.  The gene is called TMLHE and helps make the enzyme to create carnitine from methionine and lysine in the liver.

The exciting and hopeful thing about this is that carnitine is easily obtained from the diet.  It is found in RED MEAT.  There are now preparations for large scale studies to look at boys with this gene deletion in families that are either vegetarian or families where diet includes sources of carnitine.  This gene deletion is 20 times more prevalent than the gene that causes PKU, the disease that makes it difficult for a child to metabolize phenylalanine.  We are very excited because it was this very avenue of inquiry we were encouraging the NIH to pursue. We have always felt that the metabolism of the sulfur containing amino acids was a huge clue to this mystery of autism. This new connection to carnitine fits the puzzle.

Carnitine helps the body burn fat as a fuel in the mitochondtia - which are the little power plants located in each cell.  We suspect that since carnitine deficiency will create a fuel shortage - this may be why children with this deletion crave carbohydrates so noticeably.  They cannot use fat for energy - they MUST use carbohydrate.  Unfortunately the very foods they crave - Carbohydrate foods are low in carnitine - which is protein in nature.  The problem is this - ubiquitous corn - is very low in lysine - the amino acid used to make carnitine.

How does glutamate fit into all this?  Carnitine helps keep glutamate levels in the blood in check. In fact, it is being studied for preventing glutamate injury in stroke.

Do vaccines ALSO play a role here?  Well, babies are usually at risk for carnitine deficiency.  Unfortunately, before they can even be tested for this, they are given MSG containing vaccines. WE feel, like the NIH  does, that the carnitine angle is EXTREMELY important for further study and that the day they are born , children should be tested for this gene deletion and prevented from getting MSG containing vaccines. This is ANOTHER reason they need to get MSG out of the vaccines.  ASAP.

JULY 29, 2010 - The Glutamate blocking drug Memantine, used to treat Alzheimer's disease is now being used to treat Autism. According to this article, "Both Alzheimer’s disease and autism share a brain malfunction involving a chemical called glutamate, which impacts the patient’s speech and interaction. "  Their words. Our italics.  However, nobody is even going near the fact that MSG contributes to the problem in both Alzheimer's patients and autistic children, and that processed gluten and casein are very highly concentrated sources of glutamate.  It is our firm belief that DIET may very well be a part of the future successful treatment - something many parents have already known for a while, as most doctors summarily dismissed it.

The good news is, while the pharmaceutical makers are calculating how much money can be made by the sale of prescription drugs to block glutamate, a cheap and very available glutamate blocker is already widely available over the counter and has been for years.  It is called Advil. 

MAY 9, 2010 - Tylenol given with vaccines has been linked to autism:

Children given Tylenol with their vaccines were SIX TIMES more likely to develop autism than children given ibuprofen (which is a glutamate BLOCKER).  This is key - because Tylenol, like excess MSG, lowers glutathione levels. 

One of the genes for autism is for making glutathione.  Tylenol, by depleting an already low supply of glutathione, makes it more difficult for an autistic child to get rid of mercury FROM ANY SOURCE.  This finding would also imply that diet is important as well.  An MSG-laden diet after a vaccine with a Tylenol chaser would be the gift that keeps on giving - making it difficult for that child to rebuild their levels of the very important natural chelator - glutathione - regardless of whether that mercury was in a vaccine or a tuna sandwich.

November 21, 2009 - the FDA has just approved Abilify (Aripiprazole) to treat autism symptoms.  This GLUTAMATE BLOCKER is now being used to treat autism.  At the VERY SAME TIME, behavioral therapists are feeding MSG-laden junk food to children with autism as REWARDS for behavior.

Dr. Oz explains autism as a disease affected by inflammation, which is affected by DIET.

Dr. Oz didn't mention vaccines, but vaccines stimulate the immune response.  That is exactly what they are designed to do.  Unfortunately, MSG exacerbates the immune response further and most folks don't know that VACCINES are a very real source of Free Glutamic acid as well.  It is in the hydrolyzed gelatin added as a preservative in nearly all vaccines - but especially in the MMR vaccine.

For children with the RNF8 gene mutation which inhibits the formation of glutathione to begin with, the following scientific explanation of what happens in the mitochondria should be chilling enough to force the immediate removal of free glutamic acid (hydrolyzed gelatin) from all vaccines. 

According to Dr. Eduardo E. Benarroch, M.D. on Pg 296 of his book "Basic Neurosciences with Clinical Applications"

“There is a low-affinity glutamate transporter that acts as a 1:1 cystine-glutamate exchanger and carries cystine to the interior of the cell in exchange for intracellular glutamate.  The released glutamate undergoes rapid uptake via the Na+/K+ glutamate transporter.  Accumulation of extra-cellular glutamate inhibits the cystine-glutamate exchanger, resulting in depletion of cell stores of cystine.  This predisposes to oxidative stress, because cysteine, a derivative  of cystine, is required for synthesis of the anti-oxidant glutathione.  Oligodendrocytes are particularly susceptible to glutathione-induced cystine depletion and excitotoxicity.“

In recent research papers by S. H Fatemi, Autism is described as a hyper-glutamatergic disorder.  In other words, in autistic individuals, glutamate is in excess in the nervous system. 

And so based on well-accepted scientific information, children with ASD but especially those who present with heavy metal toxicity or the RNF8 mutation, and ASD symptoms of taurine deficiency (taurine is also made from cysteine) like epilepsy, irregular heartbeat, frequent diarrhea or constipation, and trouble digesting fats, should be avoiding ALL sources of excess glutamate  found in PROCESSED wheat, dairy, soy, and corn and VACCINES with any hydrolyzed protein or gelatin in them.

   FLOW CHART showing how MSG and autism are connected.

   Autism is directly impacted by genes that affect the nervous system and the neurotransmitter glutamate according to research reported in Scientific American February 17, 2007 However, because vaccines, and processed gluten and casein (wheat and dairy), are high in the amino acid glutamate in its free form, we firmly believe these items WILL affect a child's brain during development - prior to age 7.

                   =      FREE GLUTAMIC ACID (glutamate)

Autism appears very similar to the disease PKU, which causes brain damage by the buildup of the amino acid phenylalanine due to an error of metabolism that prevents the breakdown of this one amino acid.  The treatment is a special limited amino acid diet until the age of 7.

 

Based on the precedent of the disease PKU, which is tested for at birth, and treated with diet, and also involves one amino acid, we completely agree with Jenny McCarthy and her organization Generation Rescue, that the behaviors of autism can be reversed by "greening" vaccines (specifically removing glutamic acid), changing the vaccination schedule, and adhering to a strict diet limiting the excitatory amino acids glutamate and aspartate in their free form.  However, since a child's brain is generally "hard-wired" by age 7, early treatment is essential.

Carol Hoernlein wrote the following to the NIH in January. It still sums up our thoughts. It should be noted that one of the genes for autism discovered last year codes for a MITOCHONDRIAL aspartate/glutamate carrier:

"I am a former food process engineer who believes, because recent studies have implicated genes which code for glutamate synapses in ASD, we should investigate the effects of both INGESTED and INJECTED excitatory free amino acids (glutamic acid and aspartic acid) on children with these "autism genes."

If excitatory free amino acids affect ASD children, it would explain both the impact of GF-CF diets AND a vaccine link. Vaccines have free glutamic acid added to preserve the virus. I have created and attached a chart showing where free glutamic acid comes from. It is found in extremely high amounts in processed wheat and dairy products - so much so that food manufacturers use these two items routinely to produce free glutamic acid in foods but with a "clean label."

Consequently, a child may not improve on a GF-CF diet alone, because it doesn't limit all potential sources of free glutamic acid - like soy. Children are tested at birth for PKU and phenylalanine is limited until the brain is hardwired by the age of 7. Why not treat the predisposition for autism similarly and limit the glutamic and aspartic amino acids in the diets of children with autism genes?

ASD also includes errors of metabolism for sulfur containing amino acids - like cysteine. Cysteine is converted to taurine and glutathione by the liver. Taurine regulates heartbeat and osmotic balance as well as bile production and was found to be low after a seizure. In ASD, symptoms include arrhythmias, digestive disorders and a high rate of epilepsy - suggesting that taurine production may be compromised. Glutathione levels are also lower in ASD leading one to conclude that possibly, cysteine metabolism may be responsible for the myriad and seemingly unrelated additional symptoms of ASD. It should be noted that glutamate interferes with the handling of cysteine. When cysteine metabolism is compromised, homocysteine levels may increase. The lower levels of glutathione may put ASD individuals at risk of mercury poisoning, since glutathione helps eliminates mercury from the body.

It should be noted that the NMDA receptors that respond to both glutamate and aspartate are found in the amygdala - part of the limbic system involved in the perception of taste and smell as well as fear. Activating the amygdala in ASD, causes gaze avoidance. ASD children may also over-react to smells and tastes and face to face encounters can overwhelm them with fear. Limiting excitatory amino acids that target the amygdala may help.

Japan consumes more MSG, and fish (a dietary source of mercury) than nearly any other country. Compared to the amount of mercury consumed in fish and the amount of MSG consumed in the diet, the MMR contribution was probably small compared to a typical Japanese diet. In Japan, the MMR vaccine was stopped in 1993. Autism rates still increased. Perhaps in Japan, the diet plays more of a role in autism than the vaccines. Children from other countries with a lower consumption of fish and MSG may find a stronger correlation between vaccines and autism.

New research studies into ASD should include people who are sensitive to the food additives MSG and aspartame. MSG-sensitive persons have reported a distinct lessening of symptoms by using taurine, ibuprofen, CoQ10, Vitamins B6 and B12, carbohydrate, foods high in butyric acid - like butter, and Magnesium. Perhaps they share some of the same genes that predispose a child to ASD. New treatment studies should look into these easily available, inexpensive and relatively safe compounds.

Based on what I have observed, here are my recommendations:

1. Treatment of ASD?
REMOVAL of excitatory amino acids (glutamate, aspartate) from VACCINES.
Glutamate and aspartate restricted diet (similar to treatment for PKU) in addition to GF/CF diet.
Supplementation of taurine, glutathione, vitamins B6, C, magnesium, CoQ10. Increased carbohydrate.
Labeling of free glutamic and aspartic acid on food labels.
Glutamate blockers, anti-histamines and leukotriene blockers for children already suffering or getting vaccinated.
We should calm their surroundings, encourage quiet tasks and less-threatening contact to enhance communication. We need to give them space and not overwhelm them.

2. Diagnosis of ASD?
Test for autism genes preferably AT BIRTH like PKU.
Tests for aspartic acid, glutamic acid, glutathione, taurine, cysteine, homocysteine.

3. Risk factors for ASD?
Autism Genes
Sensitivity to excitatory amino acids
Low taurine,
Low glutathione
Sulfite Sensitivity
Vaccination with glutamic acid as a preservative
Damage to the microglia
Overactive immune system "Junk food" diet
Aspartame in medications or vitamins or foods
Multiple food allergy

4. Biology of ASD?
Excess CNS sensitivity,
Inability to handle sulfur-containing amino acids,
Overactive immune response - linked to Nerve Growth Factor

5. Other areas of ASD research?
Common genes in Alzheimer's, Parkinsons, ALS, MS, and excitatory amino acid sensitivity.
Study persons without ASD who suffer from overactive CNS or neurodegenerative disease and sensitivity to excitatory amino acids. See if they share same genes. Could Alzheimer's sufferers simply be ADS children whose brains were hard-wired before damage by the environment?

Thank you for this opportunity to share my ideas on this very important topic,

Please see this webpage that clearly shows why a wheat and dairy based processed food diet may be very harmful to a child sensitive to excitatory amino acids:

 http://www.msgtruth.org/avoid.htm

 

Since the above letter was written to the NIH in January, new research has uncovered 6 genes related to autism.  One specifically is involved in making glutathione (which is the body's natural chelating agent) from cysteine and glutamate.  Cysteine is one of the sulfur-containing amino acids. We were on the right track all along ......More about the AUTISM GENES.

 

On May 12, 2008 John Erb and I traveled to Washington DC to address the Federal Interagency Autism Coordinating Committee.  John and I were able to address the Committee for five minutes each - I showed and explained our flow chart while John Erb held it for me.

On the bright side, we were able to meet Margaret Dunkle who is on the forefront of efforts to actually help families dealing with autism.  Although Margaret Dunkle was unable due to time constraints, to address the Committee, I was able to obtain the statement she was going to give.  It is excellent. Here it is in its entirety:

Statement of Margaret Dunkle
Senior Fellow, Center for Health Services Research and Policy, George Washington University Director, Early Identification and Intervention Collaborative for Los Angeles CountyRecipient, American Academy of Pediatrics' Dale Richmond Award for Outstanding Achievement in the field of Child Development

May 12, 2008

Federal Interagency Autism Coordinating Committee

My name is Margaret Dunkle. Some of you know me through my current position as Senior Fellow with the Center for Health Services Research and Policy at George Washington University, and some from my prior work running policy seminars on Capitol Hill.

Some of you know me as recipient of the American Academy of Pediatrics' Dale Richmond Award for outstanding achievement in the field of child development, or for the collaborative efforts I direct in Los Angeles County to ensure all children receive good developmental screenings and effective follow-up.

More recently, some of you have come to know me because my nephew's daughter, Hannah Poling, is the little 9 -year-old girl from Athens, Georgia who was the subject of a case the government conceded in vaccine court.  The nine vaccines Hannah received on one day in July of 2000 significantly aggravated an underlying mitochondrial disorder, which predisposed her to deficits in cellular energy metabolism and manifested as a regressive encephalopathy with features of autism spectrum disorder.  Indeed, Hannah has autism, with a clear DSM-IV diagnosis based on the Diagnostic and Statistical Manual of Mental Disorders.

I believe in a strong and safe immunization program.  Yet, every day more parents and some pediatricians reject the current vaccine schedule.  I am concerned that many people are missing Hannah's clearly scribbled handwriting on the wall.  She has provided a critical clue (mitochondrial dysfunction) and a historic opportunity for our public health leaders and policymakers to act responsibly and decisively - undertaking serious science to address the very real concerns so many parents and families are raising.

Hannah's condition is not rare.  The best evidence available strongly suggests that at least 7%, and perhaps as many as 20% or 30%, of children with autism have mitochondrial dysfunction similar to Hannah's.  With one in every 150 children on the autism spectrum, these issues are both urgent and important.

Now that we know this, it is time to follow the prestigious Institute of Medicine's 2004 report that said:

"Determining a specific cause [for autism] in the individual is impossible unless the etiology is known and there is a biological marker.  Determining causality with population-based methods requires either a well-defined at-risk population or a large effect in the general population."

Mitochondrial dysfunction defining an autistic subpopulation and the role of neuro-inflammation in autism are not esoteric theories. They are real leads that need to be quickly followed.

I urge you to support the following recommendations that reflect your Committee's mission to coordinate, monitor, and recommend changes concerning federal autism efforts.

#1 First and most importantly... With Marshall Plan speed and focus, I recommend a new, intense basic science research program to get to the bottom of what is going on with the many Hannahs out there - specifically focusing on the role of mitochondrial dysfunction and neuro-inflammation in autism.

How many Hannahs with mitochondrial dysfunction are there? 4%?, 7%?, 10%?, 20%?  Where do these dysfunctions come from?  How do they work?  Can the negative effects be undone or limited?

This research must be bold, going wherever the science takes it, with nothing off the table.

I estimate $200 million will be needed to jump-start this research.  This money must be a new or redirected appropriation, not borrowed or taken from the Vaccine Injury Compensation Program (VICP).

#2 Quickly find ways to screen for and identify the subset of children like Hannah for whom vaccines can cause or exacerbate mitochondrial damage and lead to symptoms of autism.

For example, start screening the siblings of children with autism to identify biomedical markers that could lead to screening tests and treatment.

#3 Piggyback new research onto existing studies to answer important questions about autism, vaccines, mitochondrial dysfunction and neuro-inflammation.  For example:

Test alternative vaccine schedules and frequencies through the National Children's Study and use this data set of 100,000 children to get longitudinal data on these issues; and

Build new analyses into existing studies and cohorts of patients with known mitochondrial dysfunction - such as research already underway at Hopkins, the Cleveland Clinic Foundation and Columbia.

#4 Institute an immediate nationwide initiative to spot children, like Hannah, who have adverse vaccine reactions and speed them into intense early intervention (specifically, the federal IDEA Early Intervention program for children ages 0-36 months and the Preschool Education program for children ages 3-5).

An important corollary is to strengthen the Vaccine Adverse Event Reporting System (VAERS) so that it actually does the job it was set up to do - collecting information about adverse events, including "side effects," that occur after the administration of vaccines.

#5 Reform and improve the current vaccine schedule and practices to ensure they are as safe as they possibly can be.  For example, examine the number and frequency of vaccines, use of combo vaccines, preservatives used, and ages administered to identify changes that would minimize damage to children, especially susceptible children such as Hannah Poling.

It is significant that the federal Advisory Committee on Immunization Practices' recently downgraded its preference for a MMRV vaccine (four-vaccines in one shot: measles, mumps, rubella and varicella) to "no preference" because of increased seizures among children receiving the MMRV.

#6 Update the Vaccine Injury Compensation Program.  For example:

Allow parents longer than three years to file, especially given the newly identified "mitochondrial dysfunction" implications of the Hannah Poling decision and because we want parents and families to devote 100% of their energy to early intervention as soon as they learn their child has a problem; and

Update the list of "table injuries" to reflect the emerging discoveries about autism, mitochondrial dysfunction and immunological disorders.

#7 Improve the way the federal government approves and monitors vaccines and vaccine safety - perhaps establishing an independent agency (separate from the Centers for Disease Control, which also runs the National Immunization Program) to research, approve, and monitor vaccine safety and effectiveness.

****

I am proud that my family is providing hope and voice to many families across our country who have their own Hannahs.  I am also proud of their leadership to nudge those of us who care about good public health and good public policy to do the right thing and to do it right.

A little 9-year-old girl has raised incredibly tough and important questions.  Your challenge, as leaders concerned about autism, is to tackle these issues in a way that is effective and unflinching - and that responds to her clear scribbling on the wall with equally clear advances in science and improvements in immunization practices.

In addition to Margaret Dunkle, Jenny McCarthy's Generation Rescue is doing a tremendous job trying to educate parents that autism CAN BE treated and children can improve dramatically if treated as early as possible.  We also are grateful to the family of Hannah Poling for coming forward and bringing Hannah's story to the public. 

July 10, 2008, studies indicated that at least 6 genes may be related to autism.  The genes are:

1) C3orf58 - located at 3q24 (chromosome 3 - position q24)
This gene codes for a protein found in the human testes.  It was deleted in cases of autism.  The protein this codes for is not well known currently, but it is interesting that the protein is found in the male reproductive system considering that the risk of autism is greater in males than females.  It is connected to tyrosine phosphorylation and epidermal growth factor.  Is this a genetic clue as to why autism is more prevalent in males?

2) NHE9 - located at 3q24 (chromosome 3 - position q24)      
This gene codes for solute carrier family 9 members.  These proteins are linked to the CPA1 transporter family that is involved with sodium channels in the nervous system.  It is found in large amounts in the heart muscle and the skeletal muscles as well as lesser amounts in the placenta, kidney and liver, brain, medulla, and spinal cord.  It is also found in the ovary and the spleen.  It is obviously involved in the proper development and operation of the nervous system.  In persons with a mutation in this gene, ADHD symptoms may appear. 

3) PCDH10 - located at 4q283 (chromosome 4 - position q283)        
This gene codes for protocadherin 10 precursor.  This gene is involved with cell-adhesion protein, calcium ion binding and cell communication.  It is found in the brain, testes, and ovary.  Again, the nervous system and the endocrine system are involved.  Note that glutamate neurotoxicity involves calcium channels
4) CNTN3 - located at 3p26 (chromosome 3 - position p26)     
             
This gene codes for plasmacytoma associated neuronal glycoprotein.  What is fascinating about this protein is that it is found in the brain - the frontal lobe, the occipital lobe, the cerebellum, and the amygdala.  NOTE: the amygdala is what is targeted by MSG - it is involved in smell and taste as well as fear and may be responsible for the gaze-avoidance seen in autism.  It is also associated with immunoglobulin.  And so here is a link to the immune system, which in individuals with autism often is over-stimulated - resulting in multiple allergies.
 

5) RNF8 - located at 6p21.2 (chromosome 6 - position 21.2)       
This gene codes for RING finger protein 8.  What is extremely interesting about this protein is that it is used in E3 ubiquitin - protein ligase formation.  That may not mean much to you at the moment, but ligases are important in forming amino acids.  Specifically, the ones that jumped out at us here were:
a) glutamate-cysteine ligase,
b) glutathione-synthase. 
In other words, this gene is critical for the formation of glutathione.  Glutathione is the body's natural means of chelating mercury and getting rid of it.  No matter WHERE it comes from.  Could THIS gene be the reason some children with autism often suffer from heavy metal toxicity? Is THIS the common genetic source of trouble with cysteine and sulfur metabolism seen in both children with autism and those of us sensitive to MSG?

6) SCN7A - located at 2q21-q23 (chromosome 2 - position q21 - q23)            
This gene codes for proteins found in the heart and the uterus.  Mutations in this gene result in: muscle weakness, trouble swallowing, blocked and inflamed blood vessels, swelling, and erythromelalgia, (which can be caused by MERCURY POISONING, and even bromocriptine - a drug used to treat both Parkinson's and prolactin - secreting pituitary tumors.  Apparently the drug Effexor - and SSRI has been reported to relieve symptoms.)  It is interesting that mutations in this gene ALSO give the same symptoms as mercury poisoning.

Neurexin 1 - In addition, in February of 2007, it was reported that the area of the human genome found to be associated with autism, contains the genes involved in building glutamate synapses - the very locations where glutamate is used as a neurotransmitter by the nerve cells. 

The Amygdala and Fear Response in Autistic Children           

Research about autism links overstimulation of the amygdala in the brain to perceiving faces as threatening. This explains why autistic children avoid the gaze of others.

It should be noted that the NMDA receptors that respond to both glutamate and aspartate (the amino acid found in aspartame) are found in the amygdala.  The amygdala is part of the limbic system and is involved in the perception of taste and smell as well as fear. See glutamate receptors in the amygdala.
 
Could ingestion of MSG and aspartame, by targeting the amygdala, result in the perceptions and behaviors typically associated with autism?

Mercury 

Children with autism have lower levels of glutathione, and may have difficulty chelating mercury (a suspected cause of autism) and removing it from the body.  Excess glutamic acid has been proven to reduce glutathione levels that are protective against mercury poisoning.  It is our belief that the large amount of free glutamic acid still present in all vaccines today as well as increasing amounts of free glutamic acid in processed food, is responsible for the autism epidemic. 

We also believe that the mercury toxicity present in children with autism is a SIDE EFFECT of the disease, not the primary cause.  Therefore, removal of thimerosol, will not reduce the incidence of autism, because mercury is still present in our food and water, and our dental fillings, and glutamic acid is STILL in the vaccines and present in ever larger quantities in processed wheat and dairy foods.  The problem in autism is that no matter where the mercury comes from, it is not being removed as it normally should be.  The excess of mercury caused by excess glutamate, then results in heavy metal toxicity.  Considering that the newly discovered autism gene RNF8 is essential in FORMING glutathione, any additive in a vaccine that hinders glutathione formation is a not a good idea.  Therefore free glutamic acid should absolutely be removed from vaccines given to children with autism genes.

Vaccines   

MMR vaccines first came under scrutiny due to autism rates in Scotland climbing 18% in just one year. Also, other vaccines have been suspected as well. 

http://news.bbc.co.uk/1/hi/programmes/newsnight/2224126.stm

http://news.bbc.co.uk/2/hi/programmes/newsnight/2232111.stm

http://www.vaccinationnews.com/dailynews/March2002/ExpertSaysMMRWillBeProved.htm

This ingredient list of the MMR vaccine includes hydrolyzed gelatin, which contains 10% free glutamic acid.

Vaccine makers claim one "study" done in one Japanese city shows no link between autism and vaccines simply because after MMR vaccines were stopped in 1993, autism rates still rose. However, the study included only one city in a country that consumes more MSG, and fish (a dietary source of mercury) than most in the world.  Also, only one vaccine was stopped - the MMR.

Compared to the amount of mercury consumed in fish, the amount of MSG in the diet, and the amount of glutamic acid in other vaccines, the MMR contribution of mercury and glutamate was small. Autism rates in Japan still increased.

Glutamate in any vaccine WILL put children at greater risk of mercury poisoning by hindering the ability of a child to rid themselves of mercury from ANY source.  Unfortunately, free glutamic acid is found in nearly every vaccine in use today.

For more information about autism climbing and the MMR vaccine:

NOTE:  We would be remiss if we did not mention TEACCH, an organization which helps address the behaviors of autism in an effort to enable autistic children and adults to lead productive lives in society.  For while the causes of autism are still being investigated, these children are growing up and need to enter our society in meaningful ways. We should be ready to welcome them.

Gluten-Free, Casein-Free (GFCF) Diet

C
urrent treatments for autism include gluten-free and casein-free diets.  A current theory is that incomplete breakdown of gluten and casein result in the formation of casomorphins and gliadorphins, morphine-like compounds which act on the brain.  Another theory (ours) is based on the fact that 15.5% of all the amino acids in wheat are glutamic acid in its free or active form and 22.9% of the amino acids present are aspartic acid in its free and active form (which can be converted to glutamate in only one step).   In fact, wheat gluten is a considerable source of "natural" MSG in the diet.  Items containing casein, like cheese, also are high in free glutamic acid.  For example - 18.5 % of the amino acids found in cheddar cheese are free (active) glutamic acid.  Parents helping their child adhere to a strict gluten-free, casein (dairy) -free diet may wish to consider also eliminating soy products from their child's diet as well, if glutamate is suspect.

For more information about autism and diet see the following links:

Nourishing Hope - Julie Matthews Website - Certified Nutrition Consultant. We feel that Julie is doing an incredible job helping parents with nutrition challenges.

Generation Rescue - Jenny McCarthy's autism organization.

Autism Network for Dietary Intervention (ANDI)

Autism Society of America

The Autism Research Unit (Sunderland, UK) -
The Use of Gluten and Casein Free Diets with People with Autism

GFCF Diet - Gluten Free Casein Free Diet Support Group

McDonalds French Fries
Be aware that foods stating "natural flavor" on the label can be made from wheat and dairy products. As of February 22, 2006, McDonalds is in legal trouble after admitting their French fries which had been labeled gluten-free actually contain beef, wheat and dairy products due to the use of a "seasoning" placed into the oil where the fries are precooked before being shipped to restaurants.  McDonalds spokespeople don't think the fries contain enough allergens or protein to cause a problem - or to label - but consumers are angry at not being told that dairy and wheat products were involved at all.  Let the consumer be informed then they can decide to take the risk.  Parents with autistic and celiac children are furious at being deliberately misled.  Currently, there are three lawsuits pending. 

The fact that McDonalds spokespeople are stating that there is no more protein left in the "seasoning" - tells this food scientist that the entire reason for using this "seasoning" is because it probably contains free glutamic acid broken down from the high glutamate containing protein foods mentioned (beef, wheat, and milk) - another way of flavoring their fries as if they were using MSG, without having to label it as such.  Very clever, but completely unethical.

MSG symptoms and Autism symptoms have quite a lot in common:

AUTISM SYMPTOMS   

Timothy Syndrome-cardiac arrhythmia     

Rhett Syndrome which affects girls more than boys
breathing difficulty                                
speech                                               
movement                                          
Tremors                                              

Asperger's Syndrome which affects boys more than girls
ADHD                                                 
ODD                                                   
Depression                                         
Bipolar
Anxiety                                               
OCD

Heller's syndrome
Loss of communication skills                   

Common
Autism Syndrome symptoms
E
pilepsy                                              
Sensitivity to light                                 
Sensitivity to sound                               
Sensitivity to pain                               
Fatty Acid digestion problems                 
Multiple Food allergy                             
Constant motion                                   
Type I diabetes                                    
Thyroid disorder                                   
Inability to metabolize sulphur compounds  
Celiac symptoms                                    
Tantrums                                            

MSG SENSITIVITY SYMPTOMS

A-Fib (Taurine deficiency?)


Asthma
Slow speech -"Brain Fog"
"Restless Legs"
Dopamine decrease - also present with Parkinson's and pituitary tumors


ADHD symptoms
Anger/Rage
Depression

Panic



Slow speech, "Brain Fog"


S
eizures
Flashes of light
Ringing in ears - Tinnitus
Fibromyalgia, Migraine
Diarrhea/IBS
Hives, Anaphylaxis, Mastocytosis
"Restless Legs"
Type 1 diabetes with GAD immunity
Hypothyroid Disorder
Sulfite sensitivity, Taurine deficiency?
Casein, Gluten (milk and wheat) intolerance
Rage/Panic Attacks

 

 

 

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MSG and A.L.S.
MSG and Alzheimer's
MSG and Asthma
MSG and Atrial Fibrillation
MSG and Autism
MSG and Blindness
MSG and Cancer
MSG and Celiac Sprue
MSG and Depression
MSG and Diabetes
MSG and Dizziness
MSG and Epilepsy
MSG and Fibromyalgia
MSG and Heat Stroke
MSG and High Blood Pressure
MSG and Hypoglycemia
MSG and Hypothyroidism
MSG and IBS
MSG and Inflammation
MSG and Migraine
MSG and MS
MSG and Myopia
MSG and Obesity
MSG and Pituitary Tumors
MSG and Rage/Panic Disorder
MSG and Rosacea
MSG and Sulfite Sensitivity
MSG and Tinnitus
MSG and Sleeplessness

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